Changes in body weight and liver weight for control and treated Wistar female rats in the repeated dose subacute oral toxicity study (28 days)
| Experimental groups | Body weight (g) | Liver (g) | ||||
|---|---|---|---|---|---|---|
| Day 0 | Day 7 | Day 14 | Day 21 | Day 28 | ||
| Group 1 (1 × 1 mL), n = 5 | 243.2 | 265.1 | 276.5 | 292.6 | 315.2 | 12.76 |
| 257 | 272.3 | 294 | 313.7 | 335.3 | 13.77 | |
| 263.8 | 287.6 | 318.6 | 324.3 | 338 | 12.58 | |
| 268.5 | 279.4 | 299.2 | 314.9 | 336.9 | 14.62 | |
| 262.6 | 261 | 274.4 | 289.2 | 308.6 | 10.32 | |
| Group 2 (2 × 1 mL), n = 5 | 253.8 | 265.7 | 289 | 312.5 | 352 | 11.36 |
| 267.9 | 282.3 | 296.4 | 313.8 | 354 | 13.89 | |
| 258 | 280 | 301.6 | 331.7 | 366.8 | 10.88 | |
| 269 | 280.4 | 302.2 | 324.9 | 353.1 | 15.32 | |
| 255.6 | 273.1 | 294.4 | 329.24 | 340.2 | 13.5 | |
| Group 3 (3 × 2 mL), n = 5 | 235.9 | 255.8 | 277.3 | 298.5 | 325.4 | 9.89 |
| 239.7 | 257.6 | 272.3 | 294 | 330.1 | 12.36 | |
| 263.8 | 289.6 | 311.6 | 331.5 | 357 | 11.68 | |
| 265.9 | 279.8 | 294.2 | 314.9 | 351 | 13.65 | |
| 250.6 | 261.1 | 277.4 | 299.4 | 332.5 | 10.81 | |
| Control | 253.1 | 283.6 | 308.6 | 326.9 | 348.9 | 12.54 |