Changes in body weight and liver weight for control and treated Wistar male rats in the repeated dose subacute oral toxicity study (28 days)
| Experimental groups | Body weight (g) | Liver (g) | ||||
|---|---|---|---|---|---|---|
| Day 0 | Day 7 | Day 14 | Day 21 | Day 28 | ||
| Group 1 (1 × 1 mL), n = 5 | 256.9 | 316 | 335.8 | 357 | 385.6 | 16.79 |
| 268.2 | 297.6 | 320.1 | 352.9 | 380.4 | 20.02 | |
| 281.3 | 316.4 | 349.3 | 364 | 377.5 | 16.43 | |
| 265.6 | 298.1 | 324.1 | 338 | 365.9 | 17.05 | |
| 293.1 | 320.5 | 355.6 | 382.1 | 399.8 | 15.27 | |
| Group 2 (2 × 1 mL), n = 5 | 278.5 | 296.4 | 316 | 345.6 | 380.6 | 16.2 |
| 265.3 | 297.6 | 320.1 | 350.3 | 376.2 | 13.65 | |
| 281 | 290.4 | 306.9 | 320.4 | 337.1 | 9.96 | |
| 267.6 | 278.1 | 289 | 298 | 334.6 | 9.87 | |
| 293.1 | 320.5 | 356 | 375.2 | 389.5 | 14.8 | |
| Group 3 (3 × 2 mL), n = 5 | 255 | 271.3 | 289.5 | 301.5 | 299.6 | 7.57 |
| 257.2 | 281.3 | 298.6 | 330 | 365.7 | 14.35 | |
| 288.3 | 320.4 | 362.9 | 386.4 | 402.3 | 18.36 | |
| 265.2 | 298.5 | 332.5 | 360 | 386.4 | 17.35 | |
| 290.1 | 317.5 | 351.6 | 375.1 | 402 | 17.33 | |
| Control | 277.5 | 301.6 | 355.6 | 396.9 | 425 | 19.87 |