From:  Development of systolic dysfunction unrelated to myocardial infarction in treated hypertensive patients with left ventricular hypertrophy. The LIFE Study

Baseline echocardiographic characteristics of study population dichotomized by incident reduced EF

VariableNormal EF (n = 643)Reduced EF (n = 37)P
LV diameter (cm)5.14 ± 0.485.42 ± 0.650.001
LV diameter/height (cm/m)3.04 ± 0.273.18 ± 0.290.004
Relative wall thickness0.42 ± 0.060.40 ± 0.060.100
LV mass index (g/m2.7)54.1 ± 9.857.7 ± 11.60.037
LVH (%)67870.017
EF (%)64.8 ± 5.262.2 ± 5.0-
Midwall shortening (%)16.1 ± 1.815.9 ± 1.50.417
ESS (kdynes/cm2)166.5 ± 34.2171.0 ± 41.50.285
LA diameter (cm)3.88 ± 0.493.93 ± 0.680.650
Mitral E/A ratio0.84 ± 0.320.89 ± 0.400.508
E deceleration time (ms)219.0 ± 62.7232.1 ± 72.30.199
Isovolumic relaxation time (ms)113.4 ± 22.8114.6 ± 22.10.761

ANCOVA with mean values adjusted for differences in age, gender, systolic BP and heart rate. E/A ratio: the ratio of peak early (E) to late (A) diastolic transmitral blood velocity; E deceleration time: the time interval from the peak of the E wave to its projected baseline indicating the duration for equalizing the pressure difference between the LA and the left ventricle. -: P-values not calculated for components of self-reported cardiovascular diseases at baseline