Follow-up BP and echocardiographic findings in study population dichotomized by incident reduced EF
| Variable | Normal EF (n = 643) | Reduced EF | P | ||
|---|---|---|---|---|---|
| Last visit | Δ% | Last visit | Δ% | ||
| Systolic BP (mmHg) | 147 ± 20 | –15.6 | 141 ± 21 | –16.5 | 0.718 |
| Diastolic BP (mmHg) | 80 ± 11 | –13.2 | 80 ± 12 | –12.2 | 0.572 |
| LV diameter (cm) | 5.31 ± 0.45 | +3.8 | 5.73 ± 0.59 | +7.2 | 0.022 |
| Relative wall thickness | 0.33 ± 0.05 | –20.3 | 0.30 ± 0.05 | –24.3 | 0.076 |
| LV mass index (g/m2.7) | 45.9 ± 8.8 | –15.8 | 51.3 ± 11.3 | –11.2 | 0.255 |
| EF (%) | 62.9 ± 5.1 | –3.0 | 57.9 ± 4.6 | –6.9 | 0.05 |
| Midwall shortening (%) | 17.3 ± 1.6 | +8.7 | 15.0 ± 2.3 | –5.6 | 0.001 |
| ESS (kdynes/cm2) | 179.5 ± 37.5 | +10.6 | 205.1 ± 48.0 | +20.8 | 0.001 |
| LA diameter (cm) | 3.80 ± 0.55 | –1.00 | 4.14 ± 0.74 | +7.86 | 0.001 |
| Mitral E/A ratio | 0.91 ± 0.32 | +15.5 | 1.24 ± 0.98 | +48.4 | 0.001 |
| E deceleration time (ms) | 250.2 ± 66.1 | +20.4 | 234.8 ± 81.9 | +1.0 | 0.011 |
| IVRT (ms) | 95.0 ± 21.0 | –13.2 | 96.4 ± 21.3 | –13.1 | 0.974 |
On last examination before reduced EF documented; ANCOVA for differences in % change from baseline; Mean values adjusted for differences in gender, and BP and heart rate study changes; IVRT: isovolumic relaxation time