From:  Onosma L. as a source of anticancer agents: phytochemistry to mechanistic insight

Phytoconstituents procured from genus O.

Serial No.CompoundMolecular formulaMolecular weightStructurePlant usedReferences
1Hispidone (2S)-5,2′-dihydroxy-7,4′,5′-trimethoxyflavanoneC30H48O4472.70 g/moLO. hispidum[52]
27-AcetylretronecineC10H15NO3197.23 g/moLO. arenaria[3]
3Uplandicine [(7R,8R)-7-acetyloxy-5,6,7,8-tetrahydro-3H-pyrrolizin-1-yl] methyl (2R)-2,3-dihydroxy-2-[(1S)-1-hydroxyethyl]-3-methylbutanoateC17H27NO7357.40 g/moLO. arenaria[3]
4Onosmin B (methyl 2 [(4-methyl benzyl) amino] benzoate)C16H17NO2255.31 g/moLO. hispidum[55]
5Onosmin A (2-[(4-methylbenzyl) amino] benzoic acid)C15H15NO2241.28 g/moLO. hispidum[55]
6Onosmone (9R)-4,9-dihydroxy-7,12,15-trimethoxytricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3,5,7,11,13-hexaen-2-oneC18H18O6330.33 g/moLO. limitaneum[55]
7Bauerenone (4aR,6aS,6bS,8aR,11R,12S,12aR,14aR,14bR)-4,4,6a,6b,8a,11,12,14b-octamethyl-1,2,4a,5,7,8,9,10,11,12,12a,13,14,14a-tetradecahydropicen-3-oneC30H48O424.70 g/moLO. limitaneum[55]
8Ferulic acid (4-hydroxy-3-methoxy cinnamic acid)C10H10O4194.06 g/moLO. hispidum[54]
9Vanillic acid (4-hydroxy-3-methoxy benzoic acid)C8H8O4168.15 g/moLO. hispidum[54]
10Naphthoquinone 5,8-dihydroxy-2-(4-methyl-6-oxo-5,6-dihydro-2H-pyran-2-yl)-[1,4]naphthoquinoneC16H12O6300.06 g/moLO. echioides[56]
11Deoxyshikonin (5,8-dihydroxy-2-(4-methylpent-3-enyl)naphthalene-1,4-dione)C16H16O4272.30 g/moLO. echioides[56]
12Acetylshikonin [1-(5,8-dihydroxy-1,4-dioxonaphthalen-2-yl)-4-methylpent-3-enyl] acetateC18H18O6330.30 g/moLO. armeniacum[63]
131,4-naphthoquinone naphthalene-1,4-dioneC10H6O2158.02 g/moLO. echioides[64]
14Isobutyrylshikonin 1-(5,8-dimethoxy-1,4-dioxo-1,4-dihydronaphthalen-2-yl)-4-methylpent-3-en-1-yl 2-methylbutanoateC23H28O6400.19 g/moLO. visianii[65]
15Naphthoquinone (E)-2-(4-hydroxy-4-methylpent-2-en-1-yl)-5,8-dimethoxynaphthalene-1,4-dioneC18H20O5316.34 g/moLO. visianii[65]
16β,β-dimethylacrylalkanninC21H22O6370.40 g/moLO. dichroantha[66]
172,3-dihydro-3,5-dihydroxy-7-methoxyflavoneC16H14O5286.08 g/moLO. chitralicum[67]
187,4’-dihydroxy-3’-methoxyisoflavoneC16H12O5284.07 g/moLO. chitralicum[67]
19Ehretiquinone ((1R,9R,10S)-6-hydroxy-16-methyl-10-[(1E)-3-methylbuta-1,3-dienyl]-2-oxatetracyclo[7.5.3.01,10.03,8]heptadeca-3(8),4,6,12,16-pentaene-11,14-dione)C22H20O4348.14 g/moLO. bracteatum[68]
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