Exploration of Targeted Anti-tumor Therapy

Open Access Review

Metabolic plasticity drives specific mechanisms of chemotherapy and targeted therapy resistance in metastatic colorectal cancer

Mariam Rojas ... Joan Maurel

Published: September 23, 2025 Explor Target Antitumor Ther. 2025;6:1002337

DOI: https://doi.org/10.37349/etat.2025.1002337

This article belongs to the special issue Predictive and Prognostic Biomarkers in Cancer: Towards the Precision Medicine Era

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61 7 0

Open Access Original Article

Predictive value of 8-hydroxy-2′-deoxyguanosine and 8-nitroguanine production in radiation-induced skin damage after postoperative breast cancer radiotherapy

Emmanouil K. Verigos ... Dimitrios T. Trafalis

Published: September 22, 2025 Explor Target Antitumor Ther. 2025;6:1002336

DOI: https://doi.org/10.37349/etat.2025.1002336

This article belongs to the special issue Use of Different Radiation Treatment Modalities in Cancer Therapy: The Role of Inflammation and Immune Response

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116 17 0

Open Access Review

Genetic and epigenetic landscape of O⁶-methylguanine-DNA methyltransferase (MGMT): implications for DNA repair and cancer therapeutics

Shishir Singh ... Atar Singh Kushwah

Published: August 28, 2025 Explor Target Antitumor Ther. 2025;6:1002335

DOI: https://doi.org/10.37349/etat.2025.1002335

This article belongs to the special issue Advances in Cancer Genomics and Therapeutic Targets

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779 22 0

Open Access Review

Inflammatory signatures across four photon radiotherapy and proton radiotherapy: mechanisms, mitigation, and quality of life impact

Yuting Sheng ... Yujiang Fang

Published: August 28, 2025 Explor Target Antitumor Ther. 2025;6:1002334

DOI: https://doi.org/10.37349/etat.2025.1002334

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635 17 0

Open Access Review

Improvement of the sensitivity of circulating tumor DNA-based liquid biopsy: current approaches and future perspectives

Ekaterina S. Kuligina ... Evgeny N. Imyanitov

Published: August 08, 2025 Explor Target Antitumor Ther. 2025;6:1002333

DOI: https://doi.org/10.37349/etat.2025.1002333

This article belongs to the special issue Liquid Biopsy: Has Already Changed the Clinical Decision-Making in Solid Tumors Treatment?

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1821 41 0

Open Access Original Article

Anti-angiogenic effects of Moringa oleifera silver nanoparticles on endothelial cells: in vitro and ex vivo studies

Rolla Al-Shalabi ... Nozlena Abdul Samad

Published: July 27, 2025 Explor Target Antitumor Ther. 2025;6:1002332

DOI: https://doi.org/10.37349/etat.2025.1002332

This article belongs to the special issue Molecular Mechanisms and Intervention Options in Metastatic Spread of Cancer

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1479 53 0

Open Access Original Article

Correlation between histopathological features and recurrence score according to menopausal status in HR+/HER2– breast cancer patients: a retrospective study

Federica Martorana ... Paolo Vigneri

Published: July 18, 2025 Explor Target Antitumor Ther. 2025;6:1002331

DOI: https://doi.org/10.37349/etat.2025.1002331

This article belongs to the special issue Predictive and Prognostic Biomarkers in Cancer: Towards the Precision Medicine Era

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901 32 0

Open Access Original Article

Novel kinase-activating genetic events in non-small cell lung carcinomas

Elena V. Preobrazhenskaya ... Evgeny N. Imyanitov

Published: July 09, 2025 Explor Target Antitumor Ther. 2025;6:1002330

DOI: https://doi.org/10.37349/etat.2025.1002330

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914 11 0

Open Access Review

Dysbiosis and colorectal cancer: conducive factors, biological and molecular role, and therapeutic prospectives

Gurkaranjot Singh ... Vikrant Rai

Published: June 27, 2025 Explor Target Antitumor Ther. 2025;6:1002329

DOI: https://doi.org/10.37349/etat.2025.1002329

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1681 26 3

Open Access Review

Biliary tract cancers: advances in diagnostic and management

James Gutmans, Hiba Mechahougui

Published: June 23, 2025 Explor Target Antitumor Ther. 2025;6:1002328

DOI: https://doi.org/10.37349/etat.2025.1002328

This article belongs to the special issue Liquid Biopsy: Has Already Changed the Clinical Decision-Making in Solid Tumors Treatment?

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1371 26 0

Open Access Perspective

Future perspectives: targeting fibroblast growth factor receptor 1 to enhance the efficacy of immunotherapy

Ilya Tsimafeyeu

Published: June 20, 2025 Explor Target Antitumor Ther. 2025;6:1002327

DOI: https://doi.org/10.37349/etat.2025.1002327

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3282 47 0

Open Access Review

An overview of the feasibility of nanomedicine in pancreatic cancer theranostics

Kyriakos Kokkinogoulis ... Mersini Makropoulou

Published: June 18, 2025 Explor Target Antitumor Ther. 2025;6:1002326

DOI: https://doi.org/10.37349/etat.2025.1002326

This article belongs to the special issue Use of Different Radiation Treatment Modalities in Cancer Therapy: The Role of Inflammation and Immune Response

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1206 14 1

Open Access Original Article

Comparison of outcomes of neoadjuvant chemotherapy in BRCA1- versus BRCA2-associated breast and ovarian cancers

Anna Sokolenko ... Evgeny Imyanitov

Published: June 18, 2025 Explor Target Antitumor Ther. 2025;6:1002325

DOI: https://doi.org/10.37349/etat.2025.1002325

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878 7 0

Open Access Review

Osteosarcoma: current insights and advances

Guraustin S. Brar ... Yujiang Fang

Published: June 15, 2025 Explor Target Antitumor Ther. 2025;6:1002324

DOI: https://doi.org/10.37349/etat.2025.1002324

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1310 36 1

Open Access Original Article

Mutational landscape of epidermoid carcinoma of the penis in a Brazilian cohort

Renato Mendes Rossi De Lucca ... Rodolfo Borges dos Reis

Published: June 06, 2025 Explor Target Antitumor Ther. 2025;6:1002323

DOI: https://doi.org/10.37349/etat.2025.1002323

This article belongs to the special issue Predictive and Prognostic Biomarkers in Cancer: Towards the Precision Medicine Era

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1023 11 0

Open Access Review

Role of exosomes in transforming growth factor-β-mediated cancer cell plasticity and drug resistance

Tatiana Ruksha, Nadezhda Palkina

Published: June 05, 2025 Explor Target Antitumor Ther. 2025;6:1002322

DOI: https://doi.org/10.37349/etat.2025.1002322

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1054 16 2

Open Access Review

Circulating tumor cells: overcoming challenges of detecting a needle in a haystack

Zhuldyz Myrkhiyeva ... Aliya Bekmurzayeva

Published: May 29, 2025 Explor Target Antitumor Ther. 2025;6:1002321

DOI: https://doi.org/10.37349/etat.2025.1002321

This article belongs to the special issue Liquid Biopsy: Has Already Changed the Clinical Decision-Making in Solid Tumors Treatment?

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1697 26 0

Open Access Original Article

A viral circular RNA in Kaposi’s sarcoma-associated herpesvirus modulates viral and host gene expression during latent and lytic replication

Soleil Torres ... Rolf Renne

Published: May 29, 2025 Explor Target Antitumor Ther. 2025;6:1002320

DOI: https://doi.org/10.37349/etat.2025.1002320

This article belongs to the special issue Potential of Non-Coding RNAs in Cancer Research and Treatment

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1144 13 1

Open Access Review

The DNA methylation landscape of musculoskeletal sarcomas

Mariana Chantre-Justino, Walter Meohas

Published: May 26, 2025 Explor Target Antitumor Ther. 2025;6:1002319

DOI: https://doi.org/10.37349/etat.2025.1002319

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1044 17 0

Open Access Original Article

Prognostic impact of biomarkers in PMBCL: rationale for early integration of immune checkpoint inhibitors

Yana K. Mangasarova ... Andrey B. Sudarikov

Published: May 20, 2025 Explor Target Antitumor Ther. 2025;6:1002318

DOI: https://doi.org/10.37349/etat.2025.1002318

This article belongs to the special issue Immune Checkpoint Therapy and Biomarkers in Cancer

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1223 22 0