Exploration of Targeted Anti-tumor Therapy

Table 1.

Various types of nanoparticles with their beneficial attributes and limitations

Types of nanoparticles	Beneficial attributes	Limitations	References
PBCA	Low peripheral toxicity Quick biodegrading synthetic polymer Lower molecular weight	Lack of long circulating as drug carriers	[91, 92]
IONPs	High surface area to volume ratio Apt for biosensing & drug delivery Minimal toxicity Excellent superparamagnetism, biocompatibility Stability in aqueous solution	High permeability Probability of contamination Feeble bonding	[93]
FA combined with PEG	Enhances FA receptor mediated targeting delivery	Insufficient drug release Fast drug release Unstable storage	[94]
PLA nanoparticles	Sustained drug release period, biodegradable & biocompatible	Low cell adhesion biological inertness Low degradation rate Acid degradation by-products	[95]