Exploration of Targeted Anti-tumor Therapy

Table 1. Various types of nanoparticles with their beneficial attributes and limitations

Types of nanoparticles	Beneficial attributes	Limitations	References
PBCA	Low peripheral toxicity Quick biodegrading synthetic polymer Lower molecular weight	Lack of long circulating as drug carriers	[91, 92]
IONPs	High surface area to volume ratio Apt for biosensing & drug delivery Minimal toxicity Excellent superparamagnetism, biocompatibility Stability in aqueous solution	High permeability Probability of contamination Feeble bonding	[93]
FA combined with PEG	Enhances FA receptor mediated targeting delivery	Insufficient drug release Fast drug release Unstable storage	[94]
PLA nanoparticles	Sustained drug release period, biodegradable & biocompatible	Low cell adhesion biological inertness Low degradation rate Acid degradation by-products	[95]

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Declarations

Acknowledgments

The authors acknowledge Jaypee Institute of Information Technology, Noida, for providing the entire infrastructure to complete this project.

Author contributions

M Singh and DJ contributed in conceptualization, design of the work, resourcing, interpretation of data. M Singh, DJ, VA, DP, M Sharma, and PP contributed to writing—original draft, and writing—review & editing; M Singh, SM, and R contributed in supervision; M Singh, DJ, SM and R contributed in data curation, and validation.

Conflicts of interest

The authors declare that they have no conflicts of interest.

Ethical approval

Not applicable.

Consent to participate

Not applicable.

Consent to publication

Not applicable.

Availability of data and materials

Not applicable.

Funding

Not applicable.

Copyright

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