Exploration of Targeted Anti-tumor Therapy

Serial No.	Immune therapies	Observations	References
1	DCVax	Higher levels of tumor-associated antigens on GBM cells or a GBM stem cell population were linked to prolonged overall survival and progression-free survival	[96]
2	PD-1 antibody	Treatment of malignancies melanoma, is used to block the immunological checkpoint. Immune checkpoint blockade, in contrast to employing CTL to fight cancer, shuts down the immune response in a way that allows depleted CTL to attack cancer	[97]
3	MAbs (bevacizumab)	Block tumor blood vessels from growing and are also used for the treatment of a variety of cancers, including GBM	[102]
4	NCAMs	Overexpression of NK-1R in glioma tumors has led to the development of NK-1R-targeted therapies for the treatment of glioma tumors	[99]

Serial No.

Immune therapies

Observations

References

DCVax

Higher levels of tumor-associated antigens on GBM cells or a GBM stem cell population were linked to prolonged overall survival and progression-free survival

[96]

PD-1 antibody

Treatment of malignancies melanoma, is used to block the immunological checkpoint. Immune checkpoint blockade, in contrast to employing CTL to fight cancer, shuts down the immune response in a way that allows depleted CTL to attack cancer

[97]

MAbs (bevacizumab)

Block tumor blood vessels from growing and are also used for the treatment of a variety of cancers, including GBM

[102]

NCAMs

Overexpression of NK-1R in glioma tumors has led to the development of NK-1R-targeted therapies for the treatment of glioma tumors

[99]