Reported studies on PD-L1(+) CTCs in NSCLC
Authors | Pts (n) | Blood tubes | ICI | Outcome correlation |
---|---|---|---|---|
Nicolazzo et al. [38] | 24 | CellSave | N | Better if decreasing on treatment |
Guibert et al. [40] | 96 | N | Poorer if present at baseline | |
Kulasinghe et al. [41] | 33 | EDTA/Streck | N | No correlation reported |
Dhar et al. [42] | 22 | EDTA | P | Better if > 50% at baseline |
CellSave preservative tubes (Janssen) containing EDTA and a cell fixative;
not reported; pts: patients; n: number; N: nivolumab; P: pembrolizumab