Aphrodisiac activity of FD
| S/N | Methods | Solvent | Plant parts | Concentrations | Major findings | Reference |
|---|---|---|---|---|---|---|
| 1 | In vivo | Ethanol | Leaves | 125, 250, 500, and 1,000 mg/kg BW for 28 days | By enhancing fertility, reproductive hormones, and antioxidant activity, the ethanolic extract of the leaves has a positive impact on the reproduction of male mice | [100] |
| 2 | In vivo | Hot aqueous | Leaves | 0.125–4.0 mg/mL | The uterus of the isolated rat was subjected to a dose-dependent constriction by the FDA. As a result, maximum force of contraction (Emax) was lowered by all three of the drugs studied, with atosiban having a greater effect. The Emax was likewise lowered after oxodipine and ethylenediamine tetraacetic acid (EDTA) treatment. After the 2-aminoethoxydiphenyl borate (2-APB) administration, there was no noticeable difference. Thapsigargin, on the other hand, increased Emax | [101] |
| 3 | In vivo | Aqueous and ethanolic | Leaves | 800 mg/kg | Oral administration of F. deltoidea leaf aqueous and ethanolic extract improved sperm count, LDH-C 4 activity, and testosterone concentration in diabetic rats. In addition to lowering blood glucose and sperm abnormalities, these treatments had a considerable impact | [99] |
| 4 | In vivo | Methanol | Fruits | 50 mg/kg | Taking F. deltoidea dramatically improved male fertility | [102] |
| 5 | In vivo | Aqueous and ethanolic | Leaves | When rats were given an aqueous, and an ethanolic extract of F. deltoidea leaves, their testosterone level, sperm count, and mobility improved. Moreover, these treatments greatly reduced the blood glucose levels, the number of abnormal sperm, and the rate at which the blood clots. In conclusion, giving male rats an oral dose of the aqueous and ethanolic extract of F. deltoidea leaves may reverse the effects of alloxan monohydrate on blood clotting, sperm quality, and testosterone levels | [98] |