Wound healing activity of FD
| S/N | Methods | Solvent | Plant parts | Concentration | Major findings | Reference |
|---|---|---|---|---|---|---|
| 1 | In vivo | Methanol | Leaves | 20, 40, 60, and 80% | Methanolic extract of leaves at 20% concentration can heal wounds. The mice administered with an extract concentration of 80% exhibited the highest quantities of DNA and hydroxyl proline. The concentration of the extract influences how well it heals wounds | [109] |
| 2 | Scratch assays | Hot aqueous | Leaves | Leaf extract can stimulate cell growth in a dose-dependent way. Compared to cells treated with ascorbic acid and untreated cells, F. deltoidea leaf extract accelerated wound closure in scratch assays | [108] | |
| 3 | In vivo | Aqueous | Whole plants | Placebo containing 5% and 10% | Wounds treated with F. deltoidea extract containing 5 or 10% of the total extract considerably expedited the healing process compared to wounds treated with sterile deionized water | [107] |
| 4 | Aqueous, methanol, and ethanol | Leaves | 10–1,000 μg/mL | Inhibition of human liver glucuronidation activity was found in the range from 34.69 μg/mL to 398.10 μg/mL | [110] | |
| 5 | In vivo | Hot aqueous | Leaves | The liver and kidneys were unaffected by the extract. Rats treated with the extract gained weight, improved depressed behaviour, and had fewer pyknotic and dark-stained neurons in their hippocampus | [111] |