Clinicopathological features of the ESCC patients and their correlation with GDF3 gene expression
| Factor | Number (%) | GDF3 | P value | |
|---|---|---|---|---|
| Overexpression | Unchanged or underexpression | |||
| Tumor invasion | 0.032 | |||
| T1, 2 | 9 (22.5) | 1 | 8 | - |
| T3, 4 | 31 (77.5) | 6 | 25 | - |
| Metastasis | 0.964 | |||
| No metastasis | 22 (55) | 3 | 19 | - |
| Node metastasis | 18 (45) | 4 | 14 | - |
| Stage | 0.957 | |||
| I/II | 26 (65) | 3 | 23 | - |
| III/IV | 14 (35) | 4 | 10 | - |
| Grade | 0.450 | |||
| WD | 8 (20) | 2 | 6 | - |
| MD | 28 (70) | 4 | 24 | - |
| PD | 4 (10) | 1 | 3 | - |
| Tumor location | 0.828 | |||
| Middle | 21 (52.5) | 3 | 18 | - |
| Lower | 19 (47.5) | 4 | 15 | - |
| Sex | 0.174 | |||
| Male | 20 (50%) | 4 | 16 | - |
| Female | 20 (50%) | 3 | 17 | - |
-: blank cell; significant correlation; WD: well differentiated; MD: moderately differentiated; PD: poorly differentiated