Exploration of Targeted Anti-tumor Therapy

N	Parts of the plant	Solvents	Concentration	Type of cancer	Major finding	Reference
1	Leaves, roots, bark	Methanol, ethanol	-	Breast, colon	Strong action against these cancer cells and colon cancer (CC) organoids was shown by the extract. Extraction effects on triple-negative breast cancer (TNBC) cell proliferation corresponded to suppression of the Wnt3a-induced catenin stabilization and transcriptional response	[85]
2	Stem	Aqueous	1,000 mg/kg	Liver, colon, skin	50% inhibition of growth (GI₅₀) of 50 μg/mL was found to be an effective inhibitor of melanoma cell proliferation.	[86]
3	-	-	-	-	Within the first day, the IC₅₀ was 0.0008549 mg/mL. These plant extracts have antiproliferative capabilities that could be investigated	[87]

Parts of the plant

Solvents

Concentration

Type of cancer

Major finding

Reference

Leaves, roots, bark

Methanol, ethanol

Breast, colon

Strong action against these cancer cells and colon cancer (CC) organoids was shown by the extract. Extraction effects on triple-negative breast cancer (TNBC) cell proliferation corresponded to suppression of the Wnt3a-induced catenin stabilization and transcriptional response

[85]

Stem

Aqueous

1,000 mg/kg

Liver, colon, skin

50% inhibition of growth (GI₅₀) of 50 μg/mL was found to be an effective inhibitor of melanoma cell proliferation.

[86]

Within the first day, the IC₅₀ was 0.0008549 mg/mL. These plant extracts have antiproliferative capabilities that could be investigated

[87]