Exploration of Targeted Anti-tumor Therapy

Medication	Tumor type	Mechanism of action	Reference
Temozolomide	GBM and anaplastic astrocytoma	Alkylating agent that leads to methylation and later apoptosis of impacted cells	[6]
Carmustine	Glial tumors (wafers are frequently placed at the time of GBM resection as a bridge to radiation therapy)	Alkylating agent administered via intravenous injection or local implantation in wafer form	[7]
Lomustine	Glial and non-glial cell tumors like medulloblastoma	Nitrosourea works as an alkylating agent	[8, 9]

Medication

Tumor type

Mechanism of action

Reference

Temozolomide

GBM and anaplastic astrocytoma

Alkylating agent that leads to methylation and later apoptosis of impacted cells

[6]

Carmustine

Glial tumors (wafers are frequently placed at the time of GBM resection as a bridge to radiation therapy)

Alkylating agent administered via intravenous injection or local implantation in wafer form

[7]

Lomustine

Glial and non-glial cell tumors like medulloblastoma

Nitrosourea works as an alkylating agent

[8, 9]