From:  An introductory review of post-resection chemotherapeutics for primary brain tumors

Monoclonal antibodies approved for the treatment of brain tumors

MedicationTumor typeMechanism of action
BevacizumabGlial tumors which include GBM (primary and recurrent) [13]Binds to and inhibits VEGF leading to a reduction in microvascular growth which limits blood supply to tumors [14]
Naxitamab-gqgkNeuroblastoma and GD-2 positive cancers [15]Humanized monoclonal antibody [15, 16]
Dinutuximab [16]NeuroblastomaAnti-GD-2 monoclonal antibody [16]
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VEGF: vascular endothelial growth factor