From:  An introductory review of post-resection chemotherapeutics for primary brain tumors

Additional FDA-approved medication for brain tumor treatment

MedicationTumor typeMechanism of action
EvorlimusSubependymal giant cell astrocytoma (associated with tuberous sclerosis), potential applications to pediatric tumors to include DIPG, peripheral primitive neuroectodermal tumors, anaplastic astrocytomas, and ependymomas [21]Immunosuppressive macrolide that works in T-cells in response to alloantigen to stop growth-driven transduction signals [22]
BelzutifanVHL associated tumors like hemangioblastoma [23]HIF-2α inhibitor thus decreasing tumorigenesis [24]
Return to article view

DIPG: diffuse intrinsic pontine gliomas; VHL: Von Hippel-Lindau; HIF-2α: hypoxia-inducible factor-2alpha