Univariate analyses of potential viables for survival of patients with HCC
| Variables | OS | RFS | ||
|---|---|---|---|---|
| DR (95% CI) | Ptrend | TRR (95% CI) | Ptrend | |
| Age (> 48 years old vs. 48 years old)a | 0.89 (0.70–1.12) | 0.31 | 0.88 (0.69–1.12) | 0.29 |
| Gender (female vs. male) | 0.91 (0.71–1.17) | 0.47 | 0.90 (0.70–1.15) | 0.39 |
| Ethnicity (Zhuang vs. Han) | 0.81 (0.64–1.02) | 0.07 | 0.77 (0.61–1.08) | 0.08 |
| Smoking (yes vs. no) | 0.76 (0.58–0.99) | 0.05 | 0.76 (0.58–1.01) | 0.06 |
| Drinking (yes vs. no) | 0.86 (0.66–1.12) | 0.26 | 0.82 (0.63–1.08) | 0.16 |
| HBV status (positive vs. negative) | 1.04 (0.81–1.33) | 0.79 | 1.20 (0.93–1.55) | 0.16 |
| HCV status (positive vs. negative) | 1.03 (0.72–1.48) | 0.86 | 1.03 (0.71–1.50) | 0.87 |
| AFP (> 20 ng/mL vs. 20 ng/mL) | 1.11 (0.88–1.41) | 0.38 | 1.21 (0.95–1.55) | 0.13 |
| Liver cirrhosis (yes vs. no) | 1.20 (0.92–1.58) | 0.19 | 1.13 (0.85–1.49) | 0.40 |
| ES grade (high vs. low) | 1.48 (1.17–1.87) | 8.99 10–4 | 1.57 (1.24–1.99) | 2.11 × 10–4 |
| MVD (positive vs. negative) | 1.39 (1.09–1.78) | 7.30 10–5 | 1.22 (0.96–1.57) | 0.11 |
| Po-TACE treatment (yes vs. no) | 0.63 (0.50–0.80) | 9.80 10–5 | 0.61 (0.48–0.78) | 5.10 × 10–5 |
| ADAs (high vs. low)b | 3.89 (2.95–5.12) | 4.66 10–22 | 3.08 (2.36–4.02) | 1.10 × 10–16 |
a Age is grouped according to the average age of patients with HCC (47.94 years old 9.98 years old); b ADAs are grouped according to the average ADA of patients with HCC (3.00 µmol/mol 1.51 µmol/mol DNA). Ptrend: P value is calculated by trend test in the models