Multivariate analyses of potential viables for survival of patients with HCC
Variables | OS | RFS | ||
---|---|---|---|---|
DR (95% CI) | Ptrend | TRR (95% CI) | Ptrend | |
Age (> 48 years old vs. 48 years old)a | 0.94 (0.72–1.18) | 034 | 0.95 (0.70–1.28) | 0.25 |
Gender (female vs. male) | 1.00 (0.77–1.29) | 0.99 | 0.96 (0.74–1.25) | 0.76 |
Ethnicity (Zhuang vs. Han) | 0.89 (0.70–1.13) | 0.34 | 0.79 (0.61–1.01) | 0.06 |
Smoking (yes vs. no) | 0.73 (0.52–1.02) | 0.07 | 0.83 (0.59–1.17) | 0.28 |
Drinking (yes vs. no) | 0.95 (0.69–1.32) | 0.78 | 0.82 (0.58–1.15) | 0.25 |
HBV status (positive vs. negative) | 0.98 (0.75–1.29) | 0.90 | 1.16 (0.88–1.53) | 0.29 |
HCV status (positive vs. negative) | 1.01 (0.69–1.49) | 0.963 | 1.00 (0.68–1.49) | 0.99 |
AFP (> 20 ng/mL vs. 20 ng/mL) | 1.22 (0.95–1.56) | 0.13 | 1.31 (1.01–1.69) | 0.04 |
Liver cirrhosis (yes vs. no) | 1.02 (0.76–1.36) | 0.91 | 0.97 (0.72–1.29) | 0.81 |
ES grade (high vs. low) | 1.31 (1.03–1.68) | 0.03 | 1.39 (1.09–1.79) | 9.14 × 10–3 |
MVD (positive vs. negative) | 1.24 (0.95–1.62) | 0.12 | 1.09 (0.83–1.42) | 0.53 |
Po-TACE treatment (yes vs. no) | 0.59 (0.46–0.76) | 5.10 10–5 | 0.63 (0.49–0.82) | 4.36 × 10–4 |
ADAs (high vs. low)b | 3.69 (2.78–4.91) | 2.02 10–19 | 2.95 (2.24–3.88) | 1.52 × 10–14 |
a Age is grouped according to the average age of patients with HCC (47.94 years old 9.98 years old); b ADAs are grouped according to the average ADA of patients with HCC (3.00 µmol/mol 1.51 µmol/mol DNA). Ptrend: P value is calculated by trend test in the models