| CD20 positive B-NHL | CLL |
|---|---|
| Single agent to treat relapsed/refractory, low grade, or follicular B cell NHL | Combination with fludarabine and cyclophosphamide |
| Single agent therapy for those who achieve a complete or some degree of response to combination chemotherapy | |
| Single agent in low grade stable B cell NHL after CVP chemotherapy | |
| Combination with anthracycline-based chemotherapy in untreated DLBCL |
B-NHL: B cell non-Hodgkin’s lymphoma; CLL: chronic lymphocytic leukemia; DLBCL: diffuse-large B cell lymphoma