From:  Diagnostic and prognostic role of NLR in testicular cancer

General characteristics of studies on the role of NLR in tCa diagnosis

ReferenceSample sizeStudy designYear of publicationCountryHistopathologyCut off value of NLRSeminomatous tCaOutcome
Arıman and Merder [27]152Retrospective cohort2021TurkeytCa2.3952.60%NLR in healthy control group patients was significantly lower than patients with tCa.
Arda et al. [26]182Retrospective cohort2020TurkeyTGCT1.7846.60%B-HCG level was significantly higher in the patients with higher NLR.
Başer and Aras [28]83Retrospective cohort2020TurkeyTGCT2.2760.00%NLR values of the tCa patients were significantly higher than healthy controls.
Çalışkan et al. [30]285Retrospective cohort2017TurkeytCa1.6437.00%The NLR level was significantly higher in tCa group than those with benign pathology.
Kopru et al. [42]80Retrospective cohort2019TurkeytCa-51.51%Patients with tCa had a higher NLR compared to the control group with benign pathology.
Selvi and Başar [49]96Retrospective cohort2020TurkeytCa-50.00%NLR was significantly higher in patients with tCa than those with benign testis masses.
Girgin et al. [32]76Retrospective cohort2021TurkeytCa2.0634.21%The NLR values in patients with tCa were significantly higher than those with varicocele.
Gokcen et al. [33]121Retrospective cohort2018TurkeyTGCT2.25-NLR was significantly higher in patients with tCa than those with varicocele.
Kartal et al. [40]160Retrospective cohort2020TurkeyTGCT2.2543.58%NLR was significantly higher in patients with tCa than in the varicocele patients.
Şahin et al. [47]291Cross-sectional retrospective2019TurkeytCa3.16-NLR was significantly higher in patients with testicular tumor than in those with varicocele.
Yuksel et al. [54]72Retrospective cohort2016TurkeytCa2.0616.66%NLR was statistically higher in patients with tCa compared with varicocele patients.
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tCa: testicular cancer; TGCT: testicular germ cell tumor; NLR: neutrophil to lymphocyte ratio