General characteristics of studies on the role of NLR in differentiating between different types of tCa
| Reference | Sample size | Study design | Year of publication | Country | Histopathology | Cut off value of NLR | Seminomatous tCa | Outcome |
|---|---|---|---|---|---|---|---|---|
| Arıman and Merder [27] | 152 | Retrospective cohort | 2021 | Turkey | tCa | 2.39 | 52.60% | There was no statistically significant difference between cases with seminoma and non-seminomatous tCa. |
| Jankovich et al. [38] | 103 | Retrospective cohort | 2017 | Slovakia | TGCT | 4 | 39.80% | There was no statistically significant difference in NLR level between patients with seminomas and non-seminomatous tCa. |
| Kopru et al. [42] | 80 | Retrospective cohort | 2019 | Turkey | tCa | - | 51.51% | No statistically significant difference, was found in NLR of patients with seminomas and non-seminomatous tCa groups. |
| Köşeci et al. [43] | 72 | Retrospective cohort | 2021 | Turkey | TGCT | 2.5 | 43.00% | NLR level wasn’t significantly different between seminomas and non-seminomatous tCa groups. |
| Olcucu et al. [44] | 99 | Retrospective cohort | 2020 | Turkey | TGCT | 3.21 | 45.45% | There was no significant correlation between NLR and different types of tCa. |
| Horsanali et al. [36] | 128 | Retrospective cohort | 2017 | Turkey | TGCT | 3.72 | 44.80% | There was statistically significant difference in NLR between different tumor histopathology. |
tCa: testicular cancer; TGCT: testicular germ cell tumor; NLR: neutrophil to lymphocyte ratio