General characteristics of studies on the association of NLR with tumor size in tCa
| Reference | Sample size | Study design | Year of publication | Country | Histopathology | Cut off value of NLR | Seminomatous tCa | Outcome |
|---|---|---|---|---|---|---|---|---|
| Hamidi et al. [34] | 72 | Retrospective cohort | 2018 | Turkey | tCa | 2.39 | 30.50% | NLR was significantly associated with tumor size of the tCa patients. |
| Ilktac et al. [37] | 61 | Retrospective cohort | 2020 | Turkey | TGCT | 2.56 | 59.00% | A significant correlation between tumor size and NLR was reported. |
| Olcucu et al. [44] | 99 | Retrospective cohort | 2020 | Turkey | TGCT | 3.21 | 45.45% | NLR was significantly related to tumor size. |
| Kopru et al. [42] | 80 | Retrospective cohort | 2019 | Turkey | tCa | - | 51.51% | No statistically significant relationship was observed between testicular tumor size and NLR. |
| Köşeci et al. [43] | 72 | Retrospective cohort | 2021 | Turkey | TGCT | 2.5 | 43.00% | NLR was not significantly associated with tumor size. |
| Tan et al. [2] | 160 | Retrospective cohort | 2019 | Singapore | tCa | 3 | 63.80% | No difference in the tumor size between patients with different NLR values was observed. |
tCa: testicular cancer; TGCT: testicular germ cell tumor; NLR: neutrophil to lymphocyte ratio