Median OS according to KRAS and TP53 molecular profile
KRAS and TP53 molecular profile | N | Events | Median OS (95% CI) | 0.95LCL | 0.95UCL |
---|---|---|---|---|---|
KRAS-wt; TP53-wt | 20 | 15 | 16.8 (9.3–NR) | 9.3 | NR |
KRAS-m; TP53-wt | 31 | 18 | 30.4 (8.8–NR) | 8.8 | NR |
KRAS-wt; TP53-m | 33 | 20 | 23.0 (11.1–NR) | 11.1 | NR |
KRAS-m; TP53-m | 23 | 33 | 19.0 (11.1–NR) | 11.1 | NR |
TP53: tumor protein p53; KRAS: Kirsten rat sarcoma viral oncogene homolog; N: number of patients; KRAS-wt: KRAS wild type; KRAS-m: KRAS mutated; TP53-wt: TP53 wild type; TP53-m: TP53 mutated; OS: overall survival; NR: not reached. LCL: lower control limit; UCL: upper control limit