Recent clinical studies for cancer treatment by herbal medicines
| NCT number | Study phase with sponsor name | Study title | Type of condition | Treatment | Reference |
|---|---|---|---|---|---|
| NCT05897749 | Phase 4, Guang’anmen Hospital of China Academy of Chinese Medical Sciences | Clinical Study on the Effect of Brucea Javanica Oil Emulsion Injection on the Survival of Patients With Advanced Colorectal Cancer Who Failed to Receive Multi-line Treatment | Colorectal cancer | Brucea javanica oil emulsion injection | [127] |
| NCT03986528 | Phase 4, Jie Li | Clinical Trial on the Survival Advantage of Kanglaite Injection (KLTi) in Advanced Non-Small Cell Lung Cancer (NSCLC) | Non-small cell lung cancer (NSCLC) | Kanglaite injection + chemotherapy | [128] |
| NCT05229809 | Phase 4, Jie Li | Yiqi Wenyang Jiedu Prescription in the Prevention and Treatment of Postoperative Metastasis and Recurrence of Gastric Cancer: A Randomized, Double-blind, Controlled and Multi-center Clinical Study | Gastric carcinoma | Yiqi Wenyang Jiedu prescription | [129] |
| NCT01142479 | Phase 2, phase 3, Taipei City Hospital | The Effects of Compound Herbal Formula (TPE-1) for Leukopenia and Cancer-related Fatigue in Breast Cancer Patients With Radiotherapy | Breast cancer | Chinese herbal medicine decoction | [130, 131] |
| NCT04403529 | Phase 3, Fudan University | Evaluating the Clinical Value of Traditional Chinese Medicine in the Adjuvant Therapy of Triple-negative Breast Cancer | Triple negative breast cancer | Traditional Chinese medicine formulation | [132] |
| NCT03716518 | Phase 3, Xiyuan Hospital of China Academy of Chinese Medical Sciences | Effect of TCM-TSKSR on Completion Rates of Chemotherapy in Patients With Stage II & III Colon Cancer: A Randomized Placebo-Controlled Clinical Trial | Colon cancer | Tonifying spleen and kidney sequential regimen | [133] |
| NCT04546607 | Phase 2, phase 3, Natureceuticals Sdn Bhd | A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel, Study Assessing NuvastaticTM (C5OSEW5050ESA) 1,000 mg (3 Times a Day) in Improving Fatigue in Patients With Solid Stage I–IV Tumors | Astheni, cancer | Nuvastatic TM (C5OSEW5050ESA) 1,000 mg | [134, 135] |
| NCT03384667 | Phase 2, phase 3, Seong-Gyu Ko | Efficacy and Safety Evaluation of Maekmoondong-tang on Post-operative Cough in Patients With Lung Cancer -Randomized, Double-blind, Placebo-controlled Clinical Trial | Lung cancer | Maekmoondong-tang | [136, 137] |
| NCT01441752 | Phase 3, xuling | State Administration of Traditional Chinese Medicine of Shanghai | Non-small cell lung cancer | TCM | [138, 139] |
| NCT02929693 | Phase 3 | Clinical Study of Yiqi-yangyin-jiedu Decoction Combined With Gefitinib in Advanced Pulmonary Adenocarcinoma Patients With Activating EGFR Mutation | Cancer | Yiqi-yangyin-jiedu decoction | [140] |