Main human tubulin phosphorylation sites
Gene | Site | Putative kinase | Discovered by/inhibitor | Effect | Reference |
---|---|---|---|---|---|
TUBA | Ser48 | AURK | AZD1152, ZM447439 | Not known | [51] |
Ser165 | PKCα | bisindolylmaleimide | EMT | [54] | |
TUBB | Ser75 | AURK | AZD1152, ZM447439 | Not known | [51] |
TUBG | Ser131 | SadB | Targeted mutation | Centrosome duplication | [55] |
Ser385 | SadB | Targeted mutation | Promotes γ-tubulin interaction with the chromatin | [56] |
SadB: synapses of amphids defective kinase