Nociceptive TRP channels respond to environmental stimuli
| Environmental stimuli | Category | Nociceptive TRP channel | Reference | |
|---|---|---|---|---|
| Microbes | Gram-negative bacteria: bacterial endotoxins | TRPA1, TRPM3, TRPM8, TRPV1 | [81] | |
| Oncovirus | EBV | TRPA1 | [82] | |
| HBV | TRPC6 | [83] | ||
| HPV | TRPV4 | [84] | ||
| Chemicals | Mustard oil, formalin | TRPA1 | [85] | |
| Menthol, icilin | TRPM8 | |||
| DEHP | TRPV1 | [86] | ||
| Particulate matter | TRPA1, TRPC6, TRPM2, TRPV1, TRPV4 | [20] | ||
| Physical injuries | Mechanical gating | TRPA1, TRPC1, TRPC3, TRPC6, TRPM8 | [87] | |
| UVA | TRPA1 | [88] | ||
| UVB | TRPC7 | [13] | ||
EBV: Epstein-Barr virus; HBV: hepatitis B virus; HPV: human papilloma virus; UVA: ultraviolet A