Additional phosphorus dendrimers used for gene delivery of siRNAs corresponding to Figure 7
Construction | R1 | Studies | Reference |
---|---|---|---|
Plasmid and oligonucleotides | -Et | DNA delivery in HeLa and NIH 3T3 cells | [47] |
Anti-HIV siRNA | siP24 delivery in HEK293 cells | [48] | |
siRNA (siPLK1) | Delivery in MDA-MB-231 (triple-negative breast cancer) and MCF-7 cells | [49] | |
Plasmid: green fluorescent protein (GFP) reporter gene | Transfection of human stromal/mesenchymal stem cells | [50] | |
G4 phosphorus dendrimer | |||
Anti-TNFα siRNA | ![]() | In vivo via nasal administration | [51] |
HIV: human immunodeficiency virus; PLK1: polo-like kinase 1; TNFα: tumor necrosis factor alpha