From:  Targeting the two-pore channel 2 in cancer progression and metastasis

Summary of pharmacological inhibitors of TPC2 that have been pre-clinically evaluated in cancer

NameClassStructure
NaringeninFlavonoid
TetrandrineCa2+ channel blocker
Ned-19NAADP-antagonist
VerapamilCa2+ channel blocker
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Structures obtained from PubChem [83].

Note. Structure image of Naringenin is reprinted from https://pubchem.ncbi.nlm.nih.gov/compound/932#section=2D-Structure; structure image of Tetrandrine is reprinted from https://pubchem.ncbi.nlm.nih.gov/compound/73078#section=2D-Structure; structure image of Ned-19 is reprint from https://pubchem.ncbi.nlm.nih.gov/compound/3978027#section=2D-Structure; structure image of Verapamil is adapted from https://pubchem.ncbi.nlm.nih.gov/compound/2520#section=2D-Structure