Summary of broad treatment options with general indications and limitations
| Intervention | Indication | Limitations |
|---|---|---|
| Surgical resection | Single lesion resection and symptom relief | Multiple disseminated lesions |
| Whole-brain radiotherapy | High metastatic tumor load (> 10 metastases) | Off-target radiation with neurological decline |
| Stereotactic radiosurgery | Lesion diameters < 3 cm | High metastatic tumor load (> 10 metastases) |
| Systemic therapy | Therapeutic targets present | Lack of therapeutic targets |