Comparison of global 5-mC (%) between different categories of hyperprolactinemia cases and controls
| Group (n) | 5-mC (%), mean ± SD (range) | P value |
|---|---|---|
| Controls (65) | 2.82 ± 1.40 (< 0.2–6.74) | NA |
| Hyperprolactinemia patients (83) | 4.98 ± 2.68 (< 0.2–15.98) | < 0.0001** |
| Drug-induced (37) | 3.59 ± 1.91 (< 0.2–7.38) | 0.0216* |
| Idiopathic (28) | 5.94 ± 2.83 (0.63–15.98) | < 0.0001** |
| Pituitary adenoma (18) | 6.34 ± 2.44 (1.8–11.41) | < 0.0001** |
| Macroprolactinemia (20) | 5.47 ± 3.5 (< 0.2–15.98) | < 0.0001** |
| True hyperprolactinemia (63) | 4.87 ± 2.33 (0.74–8.4) | < 0.0001** |
* P < 0.05; ** P < 0.0001; NA: not applicable