Exploration of Endocrine and Metabolic Diseases

Open Access Review

Glucocorticoid receptor alpha as a core survival receptor: mechanisms, and implications for health and critical illness

G. Umberto Meduri

Published: December 01, 2025 Explor Endocr Metab Dis. 2025;2:101451

DOI: https://doi.org/10.37349/eemd.2025.101451

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Open Access Review

Psychotropic medications and metabolic side effects

Michael Natalizio ... Vikrant Rai

Published: November 24, 2025 Explor Endocr Metab Dis. 2025;2:101450

DOI: https://doi.org/10.37349/eemd.2025.101450

This article belongs to the special issue Regulators of Glucose Homeostasis, Lipid Metabolism and Energy Balance

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Open Access Commentary

The pharma race to develop increasingly more potent incretin-based therapeutics—what is for the clinicians to know

Jerzy W Kolaczynski, Eva Surmacz

Published: November 14, 2025 Explor Endocr Metab Dis. 2025;2:101449

DOI: https://doi.org/10.37349/eemd.2025.101449

This article belongs to the special issue Regulators of Glucose Homeostasis, Lipid Metabolism and Energy Balance

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Open Access Original Article

Modeling the progression of NAFLD: a multi-state Markov approach based on BMI classification in the Chinese population

Jianmin Tang ... Xinghua Yang

Published: November 13, 2025 Explor Endocr Metab Dis. 2025;2:101448

DOI: https://doi.org/10.37349/eemd.2025.101448

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Open Access Review

Hormonal changes during aging and their effects on quality of life

Carter Coggins ... Vikrant Rai

Published: November 10, 2025 Explor Endocr Metab Dis. 2025;2:101447

DOI: https://doi.org/10.37349/eemd.2025.101447

This article belongs to the special issue The Fountain of Youth: Decoding the Hormonal Regulation of Aging

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Open Access Review

Diabetes mellitus and hepatosteatosis: a narrative review

Mehmet Ali Kosekli

Published: November 10, 2025 Explor Endocr Metab Dis. 2025;2:101446

DOI: https://doi.org/10.37349/eemd.2025.101446

This article belongs to the special issue Current Views on Pathogenesis, Diagnosis and Management of Type 2 Diabetes Mellitus and Its Complications and Related Conditions

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Open Access Short Communication

Pharmacological inhibition of type 5 adenylyl cyclase, a model for healthful aging, enhanced exercise capacity and glucose tolerance

Dorothy E. Vatner ... Stephen F. Vatner

Published: November 05, 2025 Explor Endocr Metab Dis. 2025;2:101445

DOI: https://doi.org/10.37349/eemd.2025.101445

This article belongs to the special issue Innovative Strategies for Diabetes and Metabolic Disorders: Current and Future Directions

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Open Access Review

Disruption of the transsulfuration pathway as a sulfur-driven etiology of insulin resistance: proinsulin misfolding, disulfide bond deformation, and PDI dysregulation

Maher Monir Akl, Amr Ahmed

Published: November 03, 2025 Explor Endocr Metab Dis. 2025;2:101444

DOI: https://doi.org/10.37349/eemd.2025.101444

This article belongs to the special issue Current Views on Pathogenesis, Diagnosis and Management of Type 2 Diabetes Mellitus and Its Complications and Related Conditions

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Open Access Systematic Review

Clinical management strategies for type 2 diabetes mellitus with metabolic dysfunction-associated fatty liver disease: an umbrella review of systematic reviews and meta-analyses

Huiling Huang ... Dongsheng Li

Published: October 23, 2025 Explor Endocr Metab Dis. 2025;2:101443

DOI: https://doi.org/10.37349/eemd.2025.101443

This article belongs to the special issue Innovative Strategies for Diabetes and Metabolic Disorders: Current and Future Directions

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Open Access Systematic Review

Gestational diabetes mellitus in India: metabolic burden, clinical gaps, and therapeutic opportunities—a systematic review

Sumedha Rajendra Zade ... Rekha Mehani

Published: October 17, 2025 Explor Endocr Metab Dis. 2025;2:101442

DOI: https://doi.org/10.37349/eemd.2025.101442

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Open Access Original Article

Baicalin and ginsenoside Rb1 regulate the expression of adipocyte GRK2 and browning markers under lipid overload

Zhuqi Wang ... Kang Liu

Published: October 13, 2025 Explor Endocr Metab Dis. 2025;2:101441

DOI: https://doi.org/10.37349/eemd.2025.101441

This article belongs to the special issue Regulators of Glucose Homeostasis, Lipid Metabolism and Energy Balance

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Open Access Review

Metabolic syndrome in menopause

Nagamani Gumpeny ... Sridhar R. Gumpeny

Published: September 24, 2025 Explor Endocr Metab Dis. 2025;2:101440

DOI: https://doi.org/10.37349/eemd.2025.101440

This article belongs to the special issue Metabolic Syndrome in Menopause

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Open Access Systematic Review

Taste genomics and type 2 diabetes mellitus: a systematic qualitative meta-synthesis

Vishnu Shivam ... Vishnu Harish

Published: August 07, 2025 Explor Endocr Metab Dis. 2025;2:101439

DOI: https://doi.org/10.37349/eemd.2025.101439

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Open Access Meta-Analysis

Bidirectional relationship between vitamin D deficiency and type 1/type 2 diabetes mellitus: a systematic review and meta-analysis

Huiling Huang ... Dongsheng Li

Published: July 17, 2025 Explor Endocr Metab Dis. 2025;2:101438

DOI: https://doi.org/10.37349/eemd.2025.101438

This article belongs to the special issue Innovative Strategies for Diabetes and Metabolic Disorders: Current and Future Directions

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Open Access Review

Glucocorticoid signalling coordinating circadian rhythms between the glymphatic system and sleep contributes to brain health

Laura C. A. van der Zwet ... Tom Deboer

Published: July 15, 2025 Explor Endocr Metab Dis. 2025;2:101437

DOI: https://doi.org/10.37349/eemd.2025.101437

This article belongs to the special issue The HPA Axis in Health and Disease

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Open Access Original Article

Prevalence and incidence of co-morbid lung disease associated with type 2 diabetes from the UK Biobank

Roanne Lecky ... Catriona Kelly

Published: July 03, 2025 Explor Endocr Metab Dis. 2025;2:101436

DOI: https://doi.org/10.37349/eemd.2025.101436

This article belongs to the special issue Current Views on Pathogenesis, Diagnosis and Management of Type 2 Diabetes Mellitus and Its Complications and Related Conditions

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Open Access Mini Review

A comprehensive review on diabetes mellitus and heart failure

Isa Sincer

Published: June 30, 2025 Explor Endocr Metab Dis. 2025;2:101435

DOI: https://doi.org/10.37349/eemd.2025.101435

This article belongs to the special issue Current Views on Pathogenesis, Diagnosis and Management of Type 2 Diabetes Mellitus and Its Complications and Related Conditions

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Open Access Original Article

Hormone oscillations in the HPA axis: dynamical diseases and beyond

John Milton, Alexander Churilov

Published: June 24, 2025 Explor Endocr Metab Dis. 2025;2:101434

DOI: https://doi.org/10.37349/eemd.2025.101434

This article belongs to the special issue The HPA Axis in Health and Disease

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Open Access Original Article

Comparative pharmacodynamic analysis of resmetirom, semaglutide and obeticholic acid in translational mouse models of MASH

Rufeng Zhang ... Chunli Sun

Published: June 24, 2025 Explor Endocr Metab Dis. 2025;2:101433

DOI: https://doi.org/10.37349/eemd.2025.101433

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Open Access Review

Synergistic glucocorticoids, vitamins, and microbiome strategies for gut protection in critical illness

Gianfranco Umberto Meduri

Published: May 14, 2025 Explor Endocr Metab Dis. 2025;2:101432

DOI: https://doi.org/10.37349/eemd.2025.101432

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