Exploration of Endocrine and Metabolic Diseases

Open Access Short Communication

Pharmacological inhibition of type 5 adenylyl cyclase, a model for healthful aging, enhanced exercise capacity and glucose tolerance

Dorothy E. Vatner ... Stephen F. Vatner

Published: November 05, 2025 Explor Endocr Metab Dis. 2025;2:101445

DOI: https://doi.org/10.37349/eemd.2025.101445

This article belongs to the special issue Innovative Strategies for Diabetes and Metabolic Disorders: Current and Future Directions

Full Text PDF

61 7 0

Open Access Review

Disruption of the transsulfuration pathway as a sulfur-driven etiology of insulin resistance: proinsulin misfolding, disulfide bond deformation, and PDI dysregulation

Maher Monir Akl, Amr Ahmed

Published: November 03, 2025 Explor Endocr Metab Dis. 2025;2:101444

DOI: https://doi.org/10.37349/eemd.2025.101444

This article belongs to the special issue Current Views on Pathogenesis, Diagnosis and Management of Type 2 Diabetes Mellitus and Its Complications and Related Conditions

Full Text PDF

205 8 0

Open Access Systematic Review

Clinical management strategies for type 2 diabetes mellitus with metabolic dysfunction-associated fatty liver disease: an umbrella review of systematic reviews and meta-analyses

Huiling Huang ... Dongsheng Li

Published: October 23, 2025 Explor Endocr Metab Dis. 2025;2:101443

DOI: https://doi.org/10.37349/eemd.2025.101443

This article belongs to the special issue Innovative Strategies for Diabetes and Metabolic Disorders: Current and Future Directions

Full Text PDF

438 20 0

Open Access Systematic Review

Gestational diabetes mellitus in India: metabolic burden, clinical gaps, and therapeutic opportunities—a systematic review

Sumedha Rajendra Zade ... Rekha Mehani

Published: October 17, 2025 Explor Endocr Metab Dis. 2025;2:101442

DOI: https://doi.org/10.37349/eemd.2025.101442

Full Text PDF

555 17 0

Open Access Original Article

Baicalin and ginsenoside Rb1 regulate the expression of adipocyte GRK2 and browning markers under lipid overload

Zhuqi Wang ... Kang Liu

Published: October 13, 2025 Explor Endocr Metab Dis. 2025;2:101441

DOI: https://doi.org/10.37349/eemd.2025.101441

This article belongs to the special issue Regulators of Glucose Homeostasis, Lipid Metabolism and Energy Balance

Full Text PDF

455 23 0

Open Access Review

Metabolic syndrome in menopause

Nagamani Gumpeny ... Sridhar R. Gumpeny

Published: September 24, 2025 Explor Endocr Metab Dis. 2025;2:101440

DOI: https://doi.org/10.37349/eemd.2025.101440

This article belongs to the special issue Metabolic Syndrome in Menopause

Full Text PDF

1784 29 0

Open Access Systematic Review

Taste genomics and type 2 diabetes mellitus: a systematic qualitative meta-synthesis

Vishnu Shivam ... Vishnu Harish

Published: August 07, 2025 Explor Endocr Metab Dis. 2025;2:101439

DOI: https://doi.org/10.37349/eemd.2025.101439

Full Text PDF

1684 71 0

Open Access Meta-Analysis

Bidirectional relationship between vitamin D deficiency and type 1/type 2 diabetes mellitus: a systematic review and meta-analysis

Huiling Huang ... Dongsheng Li

Published: July 17, 2025 Explor Endocr Metab Dis. 2025;2:101438

DOI: https://doi.org/10.37349/eemd.2025.101438

This article belongs to the special issue Innovative Strategies for Diabetes and Metabolic Disorders: Current and Future Directions

Full Text PDF

2118 104 0

Open Access Review

Glucocorticoid signalling coordinating circadian rhythms between the glymphatic system and sleep contributes to brain health

Laura C. A. van der Zwet ... Tom Deboer

Published: July 15, 2025 Explor Endocr Metab Dis. 2025;2:101437

DOI: https://doi.org/10.37349/eemd.2025.101437

This article belongs to the special issue The HPA Axis in Health and Disease

Full Text PDF

4041 145 0

Open Access Original Article

Prevalence and incidence of co-morbid lung disease associated with type 2 diabetes from the UK Biobank

Roanne Lecky ... Catriona Kelly

Published: July 03, 2025 Explor Endocr Metab Dis. 2025;2:101436

DOI: https://doi.org/10.37349/eemd.2025.101436

This article belongs to the special issue Current Views on Pathogenesis, Diagnosis and Management of Type 2 Diabetes Mellitus and Its Complications and Related Conditions

Full Text PDF

1731 47 0

Open Access Mini Review

A comprehensive review on diabetes mellitus and heart failure

Isa Sincer

Published: June 30, 2025 Explor Endocr Metab Dis. 2025;2:101435

DOI: https://doi.org/10.37349/eemd.2025.101435

This article belongs to the special issue Current Views on Pathogenesis, Diagnosis and Management of Type 2 Diabetes Mellitus and Its Complications and Related Conditions

Full Text PDF

2504 41 0

Open Access Original Article

Hormone oscillations in the HPA axis: dynamical diseases and beyond

John Milton, Alexander Churilov

Published: June 24, 2025 Explor Endocr Metab Dis. 2025;2:101434

DOI: https://doi.org/10.37349/eemd.2025.101434

This article belongs to the special issue The HPA Axis in Health and Disease

Full Text PDF

2769 134 0

Open Access Original Article

Comparative pharmacodynamic analysis of resmetirom, semaglutide and obeticholic acid in translational mouse models of MASH

Rufeng Zhang ... Chunli Sun

Published: June 24, 2025 Explor Endocr Metab Dis. 2025;2:101433

DOI: https://doi.org/10.37349/eemd.2025.101433

Full Text PDF

3579 167 0

Open Access Review

Synergistic glucocorticoids, vitamins, and microbiome strategies for gut protection in critical illness

Gianfranco Umberto Meduri

Published: May 14, 2025 Explor Endocr Metab Dis. 2025;2:101432

DOI: https://doi.org/10.37349/eemd.2025.101432

Full Text PDF

2973 161 3

Open Access Case Report

Intravenous calcitriol: a critical intervention for severe postoperative hypoparathyroidism when oral administration is not feasible

Ignacio Jiménez Hernando ... Marta Pérez Noguero

Published: May 08, 2025 Explor Endocr Metab Dis. 2025;2:101431

DOI: https://doi.org/10.37349/eemd.2025.101431

Full Text PDF

2299 145 0

Open Access Review

Optimizing hormone replacement therapy for postmenopausal women with type 2 diabetes: a review

Butheinah A. Al-Sharafi, Samih A. Odhaib

Published: April 28, 2025 Explor Endocr Metab Dis. 2025;2:101430

DOI: https://doi.org/10.37349/eemd.2025.101430

This article belongs to the special issue Metabolic Syndrome in Menopause

Full Text PDF

6936 187 0

Open Access Case Report

Double heterozygous pathogenic variants in BRCA2 and CHEK2 in a girl with adrenocortical carcinoma

Victoria E. Fincke ... Michaela Kuhlen

Published: April 17, 2025 Explor Endocr Metab Dis. 2025;2:101429

DOI: https://doi.org/10.37349/eemd.2025.101429

Full Text PDF

1530 28 0

Open Access Commentary

Updates from the 2025 American Diabetes Association guidelines on standards of medical care in diabetes

Dipti Tiwari ... Tar Choon Aw

Published: April 15, 2025 Explor Endocr Metab Dis. 2025;2:101428

DOI: https://doi.org/10.37349/eemd.2025.101428

Full Text PDF

28406 363 0

Open Access Review

Circulating endocannabinoids and brain anatomy: unraveling the weight loss connection through lifestyle and surgery approaches

Gabrielle St-Arnaud ... Vincenzo Di Marzo

Published: April 07, 2025 Explor Endocr Metab Dis. 2025;2:101427

DOI: https://doi.org/10.37349/eemd.2025.101427

This article belongs to the special issue Regulators of Glucose Homeostasis, Lipid Metabolism and Energy Balance

Full Text PDF

2230 168 0

Open Access Review

Glucocorticoid receptor alpha: origins and functions of the master regulator of homeostatic corrections in health and critical illness

Gianfranco Umberto Meduri

Published: March 28, 2025 Explor Endocr Metab Dis. 2025;2:101426

DOI: https://doi.org/10.37349/eemd.2025.101426

Full Text PDF

2208 189 3