China and western countries are facing the double pressure of population aging and the continuous prevalence of metabolic risk factors, and the patient burden of cardiovascular disease continues to increase. In addition, patients with hypertension, dyslipidemia, and diabetes have reached hundreds of millions. In most cases, the elevation of blood pressure, blood lipid, and blood sugar levels occurs insidiously. When patients are diagnosed, vascular diseases, even myocardial infarction and stroke, have occurred. So it is tough challenging to diagnose, control and treat cardiovascular diseases.

So recent critical point of novel therapy of vascular circulation system diseases could focus on strengthen the evaluation of cardiovascular health status, the prevention and treatment of early pathological changes, non-palpation or minimal invasive diagnosis by using novel medical devices, and outstanding materials for vascular tissue engineering. We summarize the hotspot research area of cardiovascular diseases as following:

★ Perivascular medical devices and perivascular drug delivery systems, novel materials and devices for vascular interventional therapy

★ Novel medical diagnostics through a mucous tissue or membrane with minimally invasive, high-fidelity and long-term sensing interfaces

★ Biodegradable materials for directly depositing the therapy bioink at the defective organs to repair them

★ Three-dimensional (3D) bioprinting for building cardiovascular-relative organs and tissues

Keywords: Perivascular material, vascular prosthesis, intravascular stent, vascular glue and relative materials, 3D printing of cardiovascular-relative organs and tissues, diagnostics materials for cardiovascular deceases