Exploration of Asthma & Allergy

Special Issue Topic

Epidemiology of Asthma - Global Perspectives, Host and Environmental Risk Factors and Strategies for Mitigation

Submission Deadline: September 30, 2024

Guest Editor

Prof. Padukudru Anand Mahesh E-Mail

Professor, Department of Respiratory Medicine, JSS Medical College, JSSAHER, Mysore, Karnataka, India

Research Keywords: Asthma, food allergy, epidemiology, air pollution, phenotyping

About the Special Issue

Asthma is one of the most common diseases afflicting humankind and affects more than 300 million people worldwide. There is a wide variation in the prevalence of asthma among children and adults across the globe and the clear reasons for such a variation are yet to be ascertained. In this special issue, we will focus on the global variations in the prevalence of asthma, host risk factors including genetic studies, other 'omics' studies, immunology, and nutrition as well as the environmental risk factors such as indoor and outdoor air pollution, occupational factors, viral infections, microbiome, hygiene hypothesis and old friends hypothesis among others. The strategies for mitigation in preventing or reducing the global burden of asthma will be another important focus.

Keywords: Asthma, global variations, host & environmental risk factors

Call for Papers

Published Articles

Open Access

Review

Molecular mechanisms of steroid-resistant asthma
Steroid-resistant asthma (SRA) is clinically significant, approximately 10–15% of individuals with asthma do not exhibit a positive response to standard treatments. While this subset represents a [...] Read more.

Steroid-resistant asthma (SRA) is clinically significant, approximately 10–15% of individuals with asthma do not exhibit a positive response to standard treatments. While this subset represents a relatively small proportion of asthma patients, severe refractory asthma places a substantial burden on healthcare resources and contributes significantly to illness and death. Additionally, the quality of life of patients is greatly affected by the adverse effects of excessive steroid consumption, there is a need to identify individuals who do not react well to steroid medication and the ongoing difficulties of these asthma patients in controlling their diseases, which have a large socio-economic impact. The current short article reviews the common molecular mechanisms responsible for steroid resistance in asthma patients.

Mandya V. Greeshma ... Padukudru Anand Mahesh

Published: November 20, 2023 Explor Asthma Allergy. 2023;1:174–185
DOI: https://doi.org/10.37349/eaa.2023.00018

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Steroid-resistant asthma (SRA) is clinically significant, approximately 10–15% of individuals with asthma do not exhibit a positive response to standard treatments. While this subset represents a relatively small proportion of asthma patients, severe refractory asthma places a substantial burden on healthcare resources and contributes significantly to illness and death. Additionally, the quality of life of patients is greatly affected by the adverse effects of excessive steroid consumption, there is a need to identify individuals who do not react well to steroid medication and the ongoing difficulties of these asthma patients in controlling their diseases, which have a large socio-economic impact. The current short article reviews the common molecular mechanisms responsible for steroid resistance in asthma patients.

Guest Editor

About the Special Issue

Call for Papers

Published Articles