Contents
Special Issue Topic

Emerging Concepts in Subarachnoid Hemorrhage

Guest Editor

Dr. Brandon Lucke-Wold E-Mail

Department of Neurosurgery, University of Florida, Gainesville, FL 32608, USA.

Research Keywords: subarachnoid hemorrhage; neurosurgery; neurotrauma; simulation

About the Special lssue

Subarachnoid hemorrhage (SAH) continues to present serious challenges for clinicians and researchers. High morbidity and mortality exist with 1/3 of patients never making it to the hospital. As endovascular techniques have emerged, safe and more efficient aneurysm securement options are now available. The shift has become a focus on secondary mechanisms that occur after the initial hemorrhage. It is well known that vasospasm and delayed cerebral ischemia develop days to weeks after injury. What is still poorly understood is the contributory mechanisms leading to these downstream cascades. This has limited the development of effective therapeutics. This special issue will focus on those emerging topics. We are interested in both clinical and preclinical studies as well as focused reviews. Topics of particular importance include the role of microglia, the neuroinflammatory surge, and how the glymphatic system may contribute. Authors are encouraged to provide novel and innovative research to address such topics and help propel the field forward. This forum offers a unique advantage for sharing ideas and encouraging collaborative efforts.

Keywords: subarachnoid hemorrhage; neuroinflammation; vasospasm; delayed cerebral ischemia; glymphatics

Published Articles

Open Access Case Report
Tension pneumocephalus as a complication of surgical evacuation of chronic subdural hematoma: case report and literature review
Mohammed A. Azab ... Brandon Lucke-Wold
Published: August 23, 2023 Explor Neuroprot Ther. 2023;3:177–185
2874 36 0
Open Access Review
Reversible cerebral vasoconstriction syndrome: a clinical and therapeutic challenge
Andrés Ricaurte-Fajardo ... Nathalia Melo Gonzalez
Published: April 28, 2023 Explor Neuroprot Ther. 2023;3:120–130
3021 68 0
Open Access Case Report
Paraclinoid unruptured giant aneurysm with therapeutic success
Gonçalo Januário
Published: August 30, 2022 Explor Neuroprot Ther. 2022;2:174–181
3214 45 0
Open Access Review
Delayed cerebral ischemia and therapeutic approaches after subarachnoid hemorrhage
Fettah Eren ... Sueda Ecem Yilmaz
Published: August 22, 2022 Explor Neuroprot Ther. 2022;2:162–173
3913 108 2
Open Access Review
The glymphatic system and subarachnoid hemorrhage: disruption and recovery
Stephan Quintin ... Brandon Lucke-Wold
Published: June 21, 2022 Explor Neuroprot Ther. 2022;2:118–130
4140 109 10
Open Access Review
Subarachnoid hemorrhage: management considerations for COVID-19
Eric J. Panther, Brandon Lucke-Wold
Published: March 02, 2022 Explor Neuroprot Ther. 2022;2:65–73
5721 67 15