Contents
Special Issue Topic

Nanomedicine and Cancer Immunotherapy

Guest Editors

Dr. Haijun Yu E-Mail

Principal Investigator, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China

Research Keywords: Nanomedicine, immunotherapy, drug delivery, gene therapy, biomedical engineering

Dr. Yang Shi E-Mail

Group Leader, Institute for Experimental Molecular Imaging, RWTH Aachen University Clinic, Helmholtz Institute for Biomedical Engineering, Aachen, Germany

Research Keywords: Nanomedicine, immunotherapy, tumor targeting, biomaterials, biomedical engineering

About the Special lssue

Immunotherapy has shifted the paradigm of cancer research and management both in laboratory and clinic. Cancer immunotherapy with immune checkpoint inhibitors or small molecular agonists has been employed to initiate systemic and sustainable antitumor immune response for tumor regression and metastasis suppression. However, the therapeutic benefits for cancer immunotherapy are impaired by the moderate response rate and severe immune-related reverse effects. The advances of caner nanomedicine show promising potential for improving cancer immunotherapy by optimizing the pharmacokinetic profiles of immune modulators and co-delivery of multiple therapeutic agents.

In this special issue of “Nanomedicine and Cancer Immunotherapy”, we welcome both review articles and original research papers to summarize the most recent advances of nanomedicine for cancer vaccination, improved delivery of tumor antigen, delivery of small molecular immune modulators, etc. This special issue should be of high impact improving the understanding and clinical translation of nano-immunotherapy.

Keywords: Nanomedicine, cancer immunotherapy, tumor immune microenvironment, drug delivery, adaptive immune response, innate immune response

Published Articles

Open Access Review
Nano-immunotherapeutics: targeting approach as strategic regulation at tumor microenvironment for cancer treatment
Priyanka Singh ... Anita Kamra Verma
Published: February 16, 2022 Explor Med. 2022;3:22–42
2850 55 1
Open Access Review
Emerging nanomaterials for cancer immunotherapy
Sureshbabu Ram Kumar Pandian ... Krishnan Sundar
Published: June 30, 2021 Explor Med. 2021;2:208–231
3458 75 2
Open Access Review
AS1411-functionalized delivery nanosystems for targeted cancer therapy
Pooria Safarzadeh Kozani ... Mohammad Tariq Malik
Published: April 30, 2021 Explor Med. 2021;2:146–166
4638 85 3
Open Access Review
Nanomedicine in cancer therapy: promises and hurdles of polymeric nanoparticles
Carmen Paus ... Alessandra Cambi
Published: April 30, 2021 Explor Med. 2021;2:167–185
4403 83 4
Open Access Review
Cell-derived vesicles for delivery of cancer immunotherapy
Jialu Xu, Chao Wang
Published: February 28, 2021 Explor Med. 2021;2:39–59
4269 77 1