Contents
Special Issue Topic

Techniques in Repurposing and Targeted Delivery: Bringing a New Life to Shelved Drugs

Guest Editor

Dr. Md Noushad Javed E-Mail

Assistant Professor, School of Medical and Allied Sciences (SMAS), K.R. Mangalam University, Gurugram, India

About the Special lssue

Although in this current era, several promises are already translated challenges into a therapeutic solution, owing to the innovative approach of integrating existing knowledge of medical sciences with contemporary technological advancements.

Despite this, in parallel to the above, due to the emergence of new diseases, increasing complexity of existing disorders, as well as higher incidences of drug resistance; the medical fraternity and scientists are facing immense challenges with escalating of newly discovered conceptualized bench products into shelves of the clinics because of several regulatory, ethical, and financial restrictions. In order to avoid such hurdles for listing new drugs on the shelves, of late there is increasing interest in the repositioning of existing drugs, from one shelf to another with the addition of a new profile with the existing purposing.

As such practices become an important part of the drug development process and clinicians, we are here aimed to discuss the latest experimental and computation methods as well as scientific techniques as an operational approach for targeted delivery of the drugs as well as their repurposing in new inflammatory clinical indications, including cancer.

In brief, implementing a judicious and comprehensive strategy to repositioning of existing drugs would ultimately provide unique clinical, operational, as well as business opportunities.

Published Articles

Open Access Review
N-type calcium channel blockers: a new approach towards the treatment of chronic neuropathic pain
Shikha Choudhary ... Md Sabir Alam
Published: February 28, 2023 Explor Med. 2023;4:85–106
4706 87 4
Open Access Review
An overview of current strategies and future prospects in drug repurposing in tuberculosis
Dilpreet Singh ... Pooja A. Chawla
Published: February 28, 2023 Explor Med. 2023;4:71–84
2856 59 5
Open Access Original Article
Molecular docking analysis of peptide-based antiviral agents against SARS-CoV-2 main protease: an approach towards drug repurposing
Abhishek Chaurasiya ... Pooja A. Chawla
Published: February 27, 2023 Explor Med. 2023;4:33–44
3062 73 2
Open Access Review
Quality by design based development of nanostructured lipid carrier: a risk based approach
Tausif Alam
Published: December 31, 2022 Explor Med. 2022;3:617–638
2773 106 1
Open Access Review
The journey of dostarlimab: a successful weapon for cancer treatment
Rouchan Ali ... Pooja A. Chawla
Published: December 29, 2022 Explor Med. 2022;3:592–606
4153 48 0
Open Access Review
Antioxidant and photoprotective potential of Polypodium leucotomos
Rosy Yesela Mancilla Santa Cruz ... María Segunda Aurora Prado
Published: December 29, 2022 Explor Med. 2022;3:607–616
3675 76 1
Open Access Review
Role of mitochondria in brain functions and related disorders
Monu Yadav ... Anil Kumar
Published: October 31, 2022 Explor Med. 2022;3:494–515
4081 112 0
Open Access Review
Nutritional prospects of wheatgrass (Triticum aestivum) and its effects in treatment and chemoprevention
Neha Minocha ... Parijat Pandey
Published: October 12, 2022 Explor Med. 2022;3:432–442
8139 139 10