About the Special Issue

Cancer is a multifaceted and genetically diverse disease, and it continues to challenge the scientific community with its complexity. The advent of genomics has ushered in a new era of cancer research, wherein the genetic underpinnings of cancer are explored at an unprecedented resolution. This Special Issue seeks to compile the latest advancements and novel strategies in the study of cancer genomes, with the aim of elucidating the molecular orchestration that leads to tumorigenesis.

The scope of this Special Issue encompasses comprehensive research and review articles that detail the innovative use of genomic sequencing technologies, including whole-genome sequencing, exome sequencing, and targeted sequencing approaches. We encourage submissions that highlight the discovery of new genes being involved in cancer, map the cancer genome landscape, and unravel the intricacies of somatic and germline mutations in different cancers. Moreover, we welcome contributions that delve into the epigenetic modifications driving cancer progression and the genomic alterations that confer drug resistance.

In an effort to bridge the gap between genomic discoveries and clinical interventions, this issue also aims to present studies that translate genomic data into actionable therapeutic targets. Contributions may include, but are not limited to, the development of personalized medicine approaches, the identification of biomarkers for early detection, and the advancement of gene-editing technologies in cancer treatment.

This Special Issue stands at the intersection of genomics and oncology, providing a platform for researchers to disseminate their findings to a broader audience. By shedding light on the genomic blueprint of cancer, we aspire to contribute to the collective effort in combating this disease and improving patient outcomes. We invite researchers from around the globe to contribute their work to this issue, which will serve as a testament to the critical role of genomics in the ongoing battle against cancer.

Keywords: Cancer Genomics; Oncogenic Drivers; Tumor Suppressor Genes; Genomic Sequencing Technologies; Somatic Mutations; Epigenetic Alterations; Precision Oncology; Biomarker Discovery

Call for Papers