Gene therapy represents a promising approach for cancer treatment, which has shown good selectivity and efficacy in experimental system. Gene therapy refers to the introduction of genetic material into a cell to achieve a therapeutic response. Today, the gene delivery methods can be physical (e.g., microinjection, electroporation or biolistics), chemical (e.g., cationic lipid or nanoparticle carriers) or biological (e.g., viral or bacterial vectors). To achieve the high efficiency, low cytotoxicity and minimal side-effect on normal physiology, more and more novel approaches are emerging for cancer treatment. This themed issue on Gene delivery approach to fight cancer brings together some of the world's reputed experts to discuss current research and future prospects in the use of gene delivery for cancer therapy.

The potential topics for this special issue include, but are not limited to, the following:

 ★ Viral Transfection

 ★ Cationic Lipid Transfection

 ★ Polymer-based vector system

 ★ Nanovectors

 ★ Plasmid DNA

 ★ Antisense oligonucleotide

 ★ RNAi

 ★ Combinational therapy

 ★ Theranostics