Contents
Special Issue Topic

Gene Delivery Approach to Fight Cancer

Guest Editor

Prof. Xiangyang Shi E-Mail

Professor of Biomedical Engineering, College of Chemistry, Chemical Engineering and Biotechnology, Donghua University, Shanghai, China

Research Keywords: dendrimers; drug delivery; nanomedicine; theranostics; nanofibers

About the Special lssue

Gene therapy represents a promising approach for cancer treatment, which has shown good selectivity and efficacy in experimental system. Gene therapy refers to the introduction of genetic material into a cell to achieve a therapeutic response. Today, the gene delivery methods can be physical (e.g., microinjection, electroporation or biolistics), chemical (e.g., cationic lipid or nanoparticle carriers) or biological (e.g., viral or bacterial vectors). To achieve the high efficiency, low cytotoxicity and minimal side-effect on normal physiology, more and more novel approaches are emerging for cancer treatment. This themed issue on Gene delivery approach to fight cancer brings together some of the world's reputed experts to discuss current research and future prospects in the use of gene delivery for cancer therapy.

The potential topics for this special issue include, but are not limited to, the following:

 ★ Viral Transfection

 ★ Cationic Lipid Transfection

 ★ Polymer-based vector system

 ★ Nanovectors

 ★ Plasmid DNA

 ★ Antisense oligonucleotide

 ★ RNAi

 ★ Combinational therapy

 ★ Theranostics

Published Articles

Open Access Review
Macrophages as potential targets in gene therapy for cancer treatment
Yuanzheng Huang ... Xiaoxuan Liu
Published: February 28, 2023 Explor Target Antitumor Ther. 2023;4:89–101
3103 62 5
Open Access Review
Applications and challenges of biomaterial mediated mRNA delivery
Huapan Fang, Qian Chen
Published: August 31, 2022 Explor Target Antitumor Ther. 2022;3:428–444
3075 45 9
Open Access Original Article
Combination of thermal ablation by focused ultrasound, pFAR4-IL-12 transfection and lipidic adjuvant provide a distal immune response
Hai Doan Do ... Nathalie Mignet
Published: June 29, 2022 Explor Target Antitumor Ther. 2022;3:398–413
3468 97 0
Open Access Review
Polyester materials for mRNA delivery
Wang Chen ... Dandan Zhu
Published: March 11, 2022 Explor Target Antitumor Ther. 2022;3:117–127
3316 130 8
Open Access Review
Engineered phosphorus dendrimers as powerful non-viral nanoplatforms for gene delivery: a great hope for the future of cancer therapeutics
Serge Mignani ... Jean-Pierre Majoral
Published: February 25, 2022 Explor Target Antitumor Ther. 2022;3:50–61
2358 51 2